Daphne De L’Estrac
Naturopath – BHSc Naturopathy
Daphne De L’Estrac
Functional Medicine Naturopath (B.HSc) | Clinical Focus on Women’s Hormones, Gut & Skin Health
Daphne De L’Estrac is a degree-qualified Functional Medicine Naturopath with a clinical focus on complex hormonal, gastrointestinal, and dermatological conditions in women. Her evidence-based approach integrates advanced pathology, functional testing, and personalised protocols to uncover and address the root causes driving chronic symptoms.
She works primarily with women navigating conditions such as hormones and gut issues – such as PCOS, endometriosis, Hashimoto’s, perimenopause, and post-pill syndrome. Daphne also treats digestive concerns including SIBO, IBS, and gut-skin axis conditions, alongside inflammatory skin presentations such as hormonal acne and eczema.
Daphne’s method is grounded in systems-based care — recognising the bi-directional relationships between the endocrine, gastrointestinal, and immune systems. Her clinical decisions are guided by thorough investigative work, functional test interpretation, and phase-based treatment that includes nutrition, herbal medicine, and lifestyle support.
She is deeply passionate about simplifying care for her patients by identifying key nutrient deficiencies and, where appropriate, compounding personalised formulations — helping women avoid the overwhelm of long supplement lists.
Daphne created her practice as a calm, clinical space where women can step away from the noise and reconnect with their bodies. Her mission is to equip each woman with clarity, clinical insight, and the tools to stay well for the long term — with no guesswork, just root-cause resolution.
Clinical Focus
➤ Hormonal Health
- Polycystic Ovarian Syndrome (PCOS)
- Endometriosis
- Perimenopause & menopause transitions
- Hashimoto’s and subclinical hypothyroidism
- Hormonal weight gain, fatigue, low libido, and mood instability
- Amenorrhoea, irregular cycles, HRT integration, post-pill acne
➤ Gastrointestinal Health
- IBS, SIBO, food intolerances, and gut-skin axis
- Gut-hormone interactions, estrogen detoxification, liver-gut axis
- Recurrent vaginal microbiome imbalances (candida, BV, ureaplasma, biofilms)
➤ Skin & Immune Health
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Hormonal acne (cyclical, post-pill, jawline)
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Eczema and chronic inflammatory skin conditions
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Microbiome imbalances and skin barrier dysfunction
Functional Pathology & Clinical Testing
Daphne’s treatment plans are built on comprehensive functional testing to ensure precision and clarity in care. Key modalities include:
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DUTCH Hormone Testing – comprehensive sex hormone and adrenal profiling
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Gut Microbiome & SIBO Testing – including breath and stool analysis
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Organic Acids Testing (OAT) – assessing detoxification, mitochondria, and nutrient status
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Vaginal Microbiome Panels – PCR screening for persistent or biofilm-driven infections
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Methylation & Detox Profiles – supporting hormonal resilience and cognitive clarity
Each treatment plan is highly individualised, structured in clear phases, and designed to deliver real clinical outcomes.